AgeOne is backed by clinical research
Our innovation is powered by continuous investment in scientific research and clinical discovery. Every ingredient in AgeOne Daily Longevity Blend, from 500 mg β-NMN to 1.1 g glycine, 200 mg L-theanine, and 50 mg DMG, is selected for the published evidence behind it.
The result? AgeOne doesn’t just feel different. The impact is measurable.
AgeOne Daily Longevity Blend, with 18 ingredients in one daily scoop, has been put to the test in a randomised, double-blind, placebo-controlled clinical study, measuring whether the finished formula delivers meaningful nutrient biomarker changes in healthy adults.
Tested for impact on:
Our 2025 randomised, double-blind, placebo-controlled study measured meaningful changes in key blood nutrient markers after 90 days of daily AgeOne, confirming the finished formula is absorbed, not just listed on the label.
Each scoop delivers 500 mg β-NMN. In a 2023 multicentre RCT (Yi et al., GeroScience), oral NMN at 300–900 mg/day significantly raised blood NAD+ concentrations within 30–60 days versus placebo, with 500 mg sitting in the most commonly studied effective range.
DMG (50 mg), methylfolate (300 mcg), and methylcobalamin (50 mcg) are included to support homocysteine recycling and the methylation pathways NAD+ metabolism depends on. Meta-analyses of folate and B-vitamin trials confirm these nutrients reliably lower elevated homocysteine in adults.
Each scoop supplies choline (20 mg), magnesium (45 mg), biotin (100 mcg), and vitamin B1 (25 mg), nutrients involved in energy metabolism, neurotransmitter synthesis, and cognitive function. Choline is a precursor to acetylcholine; magnesium supports over 300 enzymatic reactions in the body.
Each scoop delivers 200 mg L-theanine, the exact dose used in a 2019 double-blind RCT (Hidese et al., Nutrients) where four weeks of daily L-theanine improved stress-related symptoms and cognitive function scores in healthy adults.
Our research findings
AgeOne supports healthy homocysteine levels.
Homocysteine reflects B-vitamin and methylation status. AgeOne supplies 50 mg DMG, 300 mcg methylfolate (5-MTHF), and 50 mcg methylcobalamin, nutrients shown in meta-analyses of randomised trials to support healthy homocysteine levels in adults.
AgeOne increases NAD+ precursor levels.
NAD+ is essential for cellular energy, DNA repair, and healthy ageing. Each scoop provides 500 mg β-NMN, a dose within the range studied in human RCTs (Yi et al., GeroScience, 2023) showing significant blood NAD+ increases within 30–60 days.
AgeOne supplies key structural amino acids.
Each scoop delivers 1,100 mg glycine and 300 mg MSM, structural building blocks for collagen and connective tissue. Glycine makes up roughly one-third of collagen protein, while MSM provides sulphur for keratin and collagen disulphide bonds (de Paz-Lugo et al., Amino Acids, 2018).
AgeOne supports collagen formation.
250 mg vitamin C is essential for the hydroxylation of proline and lysine in collagen synthesis. Combined with 1,100 mg glycine and 300 mg MSM, AgeOne targets the structural systems behind skin, joint, and connective tissue health (Pullar et al., Nutrients, 2017).
AgeOne supports vitamin D status.
Each scoop provides 1,000 IU vitamin D3 and 200 mcg vitamin K2 MK-7. D3 supports immune function and bone density, while K2 directs calcium to bones rather than arteries, a pairing studied for skeletal and cardiovascular health (Knapen et al., Thromb Haemost, 2015).
AgeOne supports antioxidant defence.
250 mg vitamin C and 5 mg zinc support antioxidant defence and immune function. Vitamin C is a potent antioxidant essential for collagen synthesis and immune cell function, while zinc plays a critical role in immune response, wound healing, and DNA synthesis (Prasad, Molecular Medicine, 2008).
Multicentre RCT found oral NMN at 300 to 900 mg/day significantly raised blood NAD+ concentrations within 30 to 60 days versus placebo. AgeOne provides 500 mg β-NMN per scoop.
Double-blind RCT found 200 mg/day L-theanine for four weeks improved stress-related symptoms and cognitive function scores in healthy adults. AgeOne provides 200 mg L-theanine per scoop.
Meta-analysis of randomised trials confirming folic acid and B-vitamin supplementation reliably lowers elevated homocysteine in adults, supporting AgeOne's methylfolate, DMG, and methylcobalamin stack.
Research demonstrating glycine supports collagen synthesis in connective tissue. AgeOne provides 1,100 mg glycine per scoop alongside MSM and vitamin C.
Review of vitamin C's essential role in collagen hydroxylation and skin health. AgeOne provides 250 mg vitamin C per scoop.
RCT showing vitamin K2 MK-7 supplementation improved arterial stiffness. AgeOne provides 200 mcg MK-7 alongside 1,000 IU vitamin D3.
Individual participant data meta-analysis supporting vitamin D3 supplementation for immune function. AgeOne provides 1,000 IU vitamin D3 per scoop.
Review of zinc's critical role in immune cell function, wound healing, and DNA synthesis. AgeOne provides 5 mg zinc per scoop.
Human trial confirming oral NMN is safe and efficiently raises blood NAD levels in healthy adults, supporting the NMN dose in AgeOne.
Get started from just $1.36 a day with your <<Welcome Kit>>
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| AgeOne Blend (30 Servings) | |
| 30 day supply, ships every 4 weeks | |
| First Time Purchase Includes: | |
| Storage Container | |
| Thermally & hermetically sealed storage | |
| Drink Bottle | |
| For easy measuring & shaking | |
| Total |
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AgeOne is a daily vitality drink made to support your energy, focus, gut health and immunity as you age. Each scoop brings together 18 active ingredients, including vitamins, minerals, amino acids and NMN, a precursor to NAD+, the cellular coenzyme behind your energy and repair that naturally declines as you get older.
It comes as a great-tasting powder that you mix with water, so you can replace a handful of separate supplements with one simple daily routine that supports your vitality and long-term health.
Add one level scoop (3.325 g) to a glass with around 240 ml of cold water, stir or shake well, and drink. We recommend taking AgeOne in the morning, with or without food, and finishing your drink within 30 minutes of mixing.
AgeOne has a light, refreshing berry taste, so it is easy to enjoy every day. If you prefer, you can also blend it into a cold smoothie. For the best results, take it consistently every day.
Everyone is different, and the benefits build gradually as the ingredients work with your body over time. As a general guide, many people notice steadier energy within the first week or two. Around the one-month mark, sharper focus and a more stable mood often become noticeable.
From around three months onwards, the benefits tend to be at their most consistent, as support for your cells and NAD+ levels continues to build. The key is to take AgeOne every day.
Yes. AgeOne is suitable for vegan and vegetarian diets, and it is gluten-free, dairy-free, egg-free and peanut-free. It contains no added sugar, and no artificial flavours, colours, sweeteners or preservatives. It is naturally coloured with beetroot and blue spirulina and gently sweetened with thaumatin, a natural sweetener from the katemfe fruit.
If you are pregnant, breastfeeding, taking medication or managing a health condition, we recommend checking with your doctor before starting any new supplement.
Orders are processed within 1 to 2 business days, and delivery times then vary depending on your location. You will receive tracking details by email as soon as your order is on its way.
We also stand behind AgeOne with a 30-day money-back guarantee. If you are not happy with your first order for any reason, simply get in touch within 30 days and we will make it right. If you are on a subscription, you can update, pause or cancel it at any time.
