AgeOne is backed by clinical research
Our innovation is powered by continuous investment in scientific research and clinical discovery. Every ingredient in AgeOne Daily Longevity Blend, from 500 mg β-NMN to 1.1 g glycine, 200 mg L-theanine, and 50 mg DMG, is selected for the published evidence behind it.
The result? AgeOne doesn’t just feel different. The impact is measurable.
AgeOne Daily Longevity Blend, with 18 ingredients in one daily scoop, has been put to the test in a randomised, double-blind, placebo-controlled clinical study, measuring whether the finished formula delivers meaningful nutrient biomarker changes in healthy adults.
Tested for impact on:
Our 2025 randomised, double-blind, placebo-controlled study measured meaningful changes in key blood nutrient markers after 90 days of daily AgeOne, confirming the finished formula is absorbed, not just listed on the label.
Each scoop delivers 500 mg β-NMN. In a 2023 multicentre RCT (Yi et al., GeroScience), oral NMN at 300–900 mg/day significantly raised blood NAD+ concentrations within 30–60 days versus placebo, with 500 mg sitting in the most commonly studied effective range.
DMG (50 mg), methylfolate (300 mcg), and methylcobalamin (50 mcg) are included to support homocysteine recycling and the methylation pathways NAD+ metabolism depends on. Meta-analyses of folate and B-vitamin trials confirm these nutrients reliably lower elevated homocysteine in adults.
Each scoop supplies choline (20 mg), magnesium (45 mg), biotin (100 mcg), and vitamin B1 (25 mg), nutrients involved in energy metabolism, neurotransmitter synthesis, and cognitive function. Choline is a precursor to acetylcholine; magnesium supports over 300 enzymatic reactions in the body.
Each scoop delivers 200 mg L-theanine, the exact dose used in a 2019 double-blind RCT (Hidese et al., Nutrients) where four weeks of daily L-theanine improved stress-related symptoms and cognitive function scores in healthy adults.
Our research findings
AgeOne supports healthy homocysteine levels.
Homocysteine reflects B-vitamin and methylation status. AgeOne supplies 50 mg DMG, 300 mcg methylfolate (5-MTHF), and 50 mcg methylcobalamin, nutrients shown in meta-analyses of randomised trials to support healthy homocysteine levels in adults.
AgeOne increases NAD+ precursor levels.
NAD+ is essential for cellular energy, DNA repair, and healthy ageing. Each scoop provides 500 mg β-NMN, a dose within the range studied in human RCTs (Yi et al., GeroScience, 2023) showing significant blood NAD+ increases within 30–60 days.
AgeOne supplies key structural amino acids.
Each scoop delivers 1,100 mg glycine and 300 mg MSM, structural building blocks for collagen and connective tissue. Glycine makes up roughly one-third of collagen protein, while MSM provides sulphur for keratin and collagen disulphide bonds (de Paz-Lugo et al., Amino Acids, 2018).
AgeOne supports collagen formation.
250 mg vitamin C is essential for the hydroxylation of proline and lysine in collagen synthesis. Combined with 1,100 mg glycine and 300 mg MSM, AgeOne targets the structural systems behind skin, joint, and connective tissue health (Pullar et al., Nutrients, 2017).
AgeOne supports vitamin D status.
Each scoop provides 1,000 IU vitamin D3 and 200 mcg vitamin K2 MK-7. D3 supports immune function and bone density, while K2 directs calcium to bones rather than arteries, a pairing studied for skeletal and cardiovascular health (Knapen et al., Thromb Haemost, 2015).
AgeOne supports antioxidant defence.
250 mg vitamin C and 5 mg zinc support antioxidant defence and immune function. Vitamin C is a potent antioxidant essential for collagen synthesis and immune cell function, while zinc plays a critical role in immune response, wound healing, and DNA synthesis (Prasad, Molecular Medicine, 2008).
Multicentre RCT found oral NMN at 300 to 900 mg/day significantly raised blood NAD+ concentrations within 30 to 60 days versus placebo. AgeOne provides 500 mg β-NMN per scoop.
Double-blind RCT found 200 mg/day L-theanine for four weeks improved stress-related symptoms and cognitive function scores in healthy adults. AgeOne provides 200 mg L-theanine per scoop.
Meta-analysis of randomised trials confirming folic acid and B-vitamin supplementation reliably lowers elevated homocysteine in adults, supporting AgeOne's methylfolate, DMG, and methylcobalamin stack.
Research demonstrating glycine supports collagen synthesis in connective tissue. AgeOne provides 1,100 mg glycine per scoop alongside MSM and vitamin C.
Review of vitamin C's essential role in collagen hydroxylation and skin health. AgeOne provides 250 mg vitamin C per scoop.
RCT showing vitamin K2 MK-7 supplementation improved arterial stiffness. AgeOne provides 200 mcg MK-7 alongside 1,000 IU vitamin D3.
Individual participant data meta-analysis supporting vitamin D3 supplementation for immune function. AgeOne provides 1,000 IU vitamin D3 per scoop.
Review of zinc's critical role in immune cell function, wound healing, and DNA synthesis. AgeOne provides 5 mg zinc per scoop.
Human trial confirming oral NMN is safe and efficiently raises blood NAD levels in healthy adults, supporting the NMN dose in AgeOne.
Get started from just $1.36 a day with your <<Welcome Kit>>
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| AgeOne Blend (30 Servings) | |
| 30 day supply, ships every 4 weeks | |
| First Time Purchase Includes: | |
| Storage Container | |
| Thermally & hermetically sealed storage | |
| Drink Bottle | |
| For easy measuring & shaking | |
| Total |
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AgeOne® Daily Longevity Blend combines 18 longevity ingredients, including 500 mg β-NMN, 1.1 g glycine, 200 mg L-theanine, 50 mg DMG, and vitamins D3, K2, and methylated B vitamins, to target the six areas most affected by ageing: energy, metabolism, hormones, structure, recovery, and defence.
NMN (nicotinamide mononucleotide) is a direct precursor to NAD+, a molecule central to cellular energy and healthy ageing. Each scoop provides 500 mg β-NMN. Human RCTs (Yi et al., GeroScience, 2023) show oral NMN significantly raises blood NAD+ within 30–60 days. DMG (50 mg), methylfolate (300 mcg), and methylcobalamin (50 mcg) are included alongside NMN to support the methylation pathways NAD+ metabolism depends on.
Yes. In 2025, AgeOne Daily Longevity Blend completed a randomised, double-blind, placebo-controlled clinical study measuring nutrient biomarkers, including homocysteine and NAD+ precursors, in healthy adults over 90 days. Each of the 18 ingredients is also backed by published peer-reviewed research. Every batch is independently tested for purity, potency, and label accuracy.
Many customers report steadier energy and sharper focus within the first few weeks. NAD+ replenishment is a cellular process, so consistency matters. One scoop every morning is the best way to see results.
Every ingredient in AgeOne has been selected based on published studies. Visit our Ingredients page to explore each ingredient's dose, form, and key references, from NMN and DMG to glycine, L-theanine, MSM, and zinc.
We offer a 30-day money-back guarantee. If AgeOne is not right for you, contact us within 30 days of delivery.
